IGF2BP2 and IGF2BP3 augmented the stability of DDX21 mRNA in an m6A-dependent manner, followed by recruitment of transcription factor YBX1 by DDX21 on ULK1 gene promoter and elevated transcription of ULK1, which facilitates progression of acute myeloid leukemia [26]. The gene discussed is IGF2BP2; the disease is acute myeloid leukemia.