AKT1 and neoplasm: The study of PCNA levels, involved in DNA replication, cell division, DNA repair and also cytosolic metabolic activities, that is, glycolysis, pentose phosphate pathway, and Akt signalling, thus being associated with tumour aggressiveness [17], indicated that the promising effects on survival at 48 h of treatment were corroborated, highlighting the superior efficacy of the new platinum compound over Cisplatin.