MMP10, also known as matrix metalloproteinase 10 or stromelysin 2, is a protease encoded by the human MMP10 gene.[39] MMP10 is mainly involved in the degradation of extracellular matrix, especially proteoglycans and fibronectin.[40] Although it plays an important role in various physiological and pathological processes including tissue remodeling and repair, cell migration, inflammatory response, and tumor progression,[41, 42] few studies have addressed the potential relationship between MMP10 and vascular calcification. Here, MMP10 is linked to neoplasm.