Furthermore, compared with the results of pathway enrichment analysis for other cancers, we found that several pathways in HCC also share some commonalities with other cancers, including the cell cycle, DNA repair, the p53 pathway, and chromatin remodeling, which may be closely related to the promotion of cancer development by RIOK1 (Figure S3B–F). This evidence concerns the gene RIOK1 and hepatocellular carcinoma.