Thus, to determine the trade‐off between NK cell proliferation and degranulation or cytokine release in our culture conditions, we plotted average proliferation on day 9 as a function of the average %CD107a and %IFNγ expressions across HCC cell lines HepG2, PLC and SNU475 on day 10, which was the closest to the observed day of the proliferation measurement. This evidence concerns the gene IFNG and hepatocellular carcinoma.