In mice, mutant Lrp1R1783W homozygote and heterozygote mice exhibited delayed Y-shaped triradiate cartilage and smaller acetabulum in 8-week and 16-week-old mice, respectively.32 Heterozygous global Lrp1 knockout (KO) mice also developed a hip dysplasia phenotype. Here, LRP1 is linked to Hip dysplasia.