Additionally, in comparison with non-AKI group, the cases of AKI group showed the higher levels of C-reactive protein CRP (p = 0.001), PCT (p < 0.001), lactate (p < 0.001), AST (p = 0.003), ALT (p = 0.049), total bilirubin (p = 0.034), BNP (p = 0.019) and cTnI (p = 0.012). The gene discussed is NPPB; the disease is acute kidney injury.