It can promote anti-tumor immunity by inducing the proliferation of CTLs, such as CD8+ T cells and natural killer (NK) cells.3–5,14,18 IFN-γ plays a central role in coordinating and balancing innate and adaptive immunity by activating the immune responses to eliminate pathogens and tumors and preventing immune over-activation with associated, nonspecific tissue damage. Here, IFNG is linked to neoplasm.