Xue and collaborators showed that ω-3 PUFAs significantly reduced the β-catenin levels and the expression of the Wingless-related integration site (Wnt)/β-catenin targets genes, such as c-myc and cyclin D1, in mammary tumors from female outbred Babl/c mice injected with 4T1 mouse breast cancer cells [102]. Here, CCND1 is linked to breast cancer.