Red rectangles represent the hit genes involved in the treatment of tongue cancer (TERT, Bcl-2, CDK4/6, CDK2, VEGF, ER, RXR,c-KIT, MET, FGFR, PPAR8, PFFP, MMPs, CDK4, AR, F2, IGFR). The gene discussed is CDK2; the disease is tongue cancer.