Further, the correlation analysis of AhR and FTO expression in 169 glioblastoma samples revealed that AhR expression was negatively correlated with FTO expression (R = −0.238, p = 0.008) (Fig. 5E), indicating that IDO1 inhibits FTO activity by promoting AhR expression and nuclear translocation. The gene discussed is IDO1; the disease is glioblastoma.