Previously, ZBP1-mediated PANoptosis has been proven to play a vital role in many infectious diseases by promoting cell death and inflammation to activate host defense or inflammatory tissue damage, such as C. albicans, A. fumigatus [44], SARS-CoV-2 [49, 50], influenza A virus [51, 52] and Yersinia infections [34]. Here, ZBP1 is linked to Yersinia infectious disease.