Underlining the tumour-suppressing role of infiltrating T-cells, the difference in median overall survival significantly expanded from 7 days in immunocompetent (Fig. 3D) to 29 days in athymic nude mice (44 days (Cx3cl1+) vs. 73 days (Ctrl), P = 0.008; Fig. 3H). Here, CX3CL1 is linked to neoplasm.