Thus, in contrast to its favourable prognostic role in other cancer entities and in contrast to the positive prognostic impact of other T-cell and NK cell recruiting chemokines (e.g. CXCL9 and CXCL10) in ovarian cancer, elevated CX3CL1 levels are associated with worsened outcome in HGSOC. The gene discussed is CX3CL1; the disease is ovarian cancer.