In accordance with our in vitro data (Fig. 3B), enhanced proliferation did not seem to account for the accelerated tumour outgrowth upon Cx3cl1 overexpression, as Ki67-positivity was unaltered in Cx3cl1+ tumours (median 37 % vs 36 % of total cells; P = 0.76; Fig. 3G). Here, MKI67 is linked to neoplasm.