Thus, in contrast to its favourable prognostic role in other cancer entities and in contrast to the positive prognostic impact of other T-cell and NK cell recruiting chemokines (e.g. CXCL9 and CXCL10) in ovarian cancer, elevated CX3CL1 levels are associated with worsened outcome in HGSOC. Here, CX3CL1 is linked to ovarian carcinoma.