Thus, in contrast to its favourable prognostic role in other cancer entities and in contrast to the positive prognostic impact of other T-cell and NK cell recruiting chemokines (e.g. CXCL9 and CXCL10) in ovarian cancer, elevated CX3CL1 levels are associated with worsened outcome in HGSOC. This evidence concerns the gene CX3CL1 and cancer.