Compared to the ID8-Trp53-/- control group, Cx3cl1+ tumours contained approximately 30 % more intratumoural CD3-positive (P = 0.050) and CD8-positive T-cells (P = 0.040), whereas no difference was seen in the amount of intratumoural Granzyme-B expressing cells (P = 0.589; Fig. 3F). The gene discussed is GZMB; the disease is neoplasm.