This finding was further confirmed using CUT&Run followed by qPCR analysis, which demonstrated IKZF1 binding at the BCL-2 promoter in both CEM (p = .0008) and MOLT-4 (p = .0381) cell lines, as well as in primary T-ALL cells (p = .0151) (Figure 1b). This evidence concerns the gene BCL2 and acute lymphoblastic leukemia.