The median (IQR)s of white cell count, protein, neopterin, and CXCL-10 in HAM (Group A) were still higher than those in the non-neuroinflammatory (Group C) (p < 0.05), and the median (IQR) of HTLV-1 proviral load in CSF was 7.6 (1.57–12.7) copies/mL. Here, CXCL10 is linked to tropical spastic paraparesis.