CD8A and COVID-19: Moreover, when we performed a paired analysis between the time points of the disease onset (T0) and the last follow-up visit after 12 months (T6), non-COVID-19 (PCR-Pn+) patients displayed a significant difference in the naïve CD8+ T cells between them, suggesting a “reactive” increase in these cells in the acute phase and, then, a return to their steady state over time.