Hepatitis flare with an increase in ALT levels was observed in 10.7% of the studied population (again, not in patients being treated with NAs) and occurred more frequently in HBsAg-positive/anti-HBc-positive (16.7%) and HBsAg-negative/anti-HBc-positive/anti-HBs-negative (16.0%) patients than in HBsAg-negative/anti-HBc-positive/anti-HBs-positive subjects (p = 0.003). Here, KRT88P is linked to Hepatitis.