ACE2 and COVID-19: Moreover, as reported in Daniell et al. [12,19], the ACE2 gum efficiently debulked the SARS-CoV-2 virus count by >95% in COVID-19 patient saliva and nasopharyngeal swab samples by the direct binding of the spike protein to soluble ACE2, as measured by microbubbling (N antigen), a RAPID (spike protein) assay, and qPCR, demonstrating both virus trapping and the blocking of cellular entry.