The combined use of both compounds in vitro modulated, among others, the expression of cellular inhibitor of apoptosis 2 (cIAP2), proapoptotic caspase 7, oncogenic miRNA-221/222, and tumor suppressors p27 and PTEN, and finally reduced the metastatic potential and migration of cancer cells [122,123]. This evidence concerns the gene BIRC3 and neoplasm.