In studies on the model of cerebral ischemia in rats, the endothelioprotective activity of Angiolin was also demonstrated, i.e., an increase in the density of endotheliocytes of muscle-type vessels and microcirculatory channel, an increase in the density of proliferating endotheliocytes, and an increase in the expression of vascular endothelial growth factor (VEGF) and receptor-binding coefficient [11,18]. Here, VEGFA is linked to Cerebral ischemia.