Interestingly, the majority of susceptibility genes associated with GDM relate to β-cell functions and pancreas development, including the potassium voltage-gated channel KQT-like 1 (KCNQ1), CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1), melatonin receptor 1B (MTNRB1), and glucokinase (GCK) [6]. The gene discussed is GCK; the disease is gestational diabetes.