Ulubasoglu et al. [50] observed that patients with GDM had lower serum SIRT1 levels during the second trimester of pregnancy: 22.0 (19.9–24.3) ng/mL in the GDM group and 34.7 (28.8–54.6) ng/mL in the control/healthy group. Here, SIRT1 is linked to gestational diabetes.