NFKB1 and colorectal carcinoma: In colorectal cancer (CRC), it exerts its therapeutic effects through mechanisms such as downregulating pro-inflammatory cytokines, suppressing nuclear factor-kappa B (NF-κB) activity—a key regulator of inflammation and tumorigenesis—and inhibiting the Wnt/β-catenin signaling pathway, a crucial driver of CRC progression and metastasis [48,49,50,51,52].