To investigate the effects of the Terpinen-4-ol on gouty arthritis, the target genes of Terpinen-4-ol network and the ‘gout’ gene set were compared, resulting in the deduction of eight intersecting genes, including NLRP3, PTGS2, CXCL8, IL6, TNF, IL1B, TLR4, and ALB (Figure 3C). This evidence concerns the gene TLR4 and gout.