The effect of TT on these genes not only has a therapeutic effect on neurodegenerative diseases but also on endocrine, dermatological, cardiovascular, digestive, respiratory, gynecological, and rheumatoid diseases (Asiatic acid impact on AKT, mTOR, NF-κB, BDNF, CPT-1, SOX2, BCL2, IL18, CASP-3, and NLRP3 modulates the therapeutic effect for some neurological, digestive, dermatological, endocrine, cardiovascular, and respiratory conditions. This evidence concerns the gene IL18 and neurodegenerative disease.