In the cases of dilated cardiomyopathy, cardiac muscle contraction, and hypertrophic cardiomyopathy (B), seven downregulated proteins were enriched, including Myl2, Myl3, Myh7, Atp2a1, Tpm1, Tpm2, and Ttn (Figure 10). The gene discussed is TPM2; the disease is dilated cardiomyopathy.