TPM1 and hypertrophic cardiomyopathy: In the cases of dilated cardiomyopathy, cardiac muscle contraction, and hypertrophic cardiomyopathy (B), seven downregulated proteins were enriched, including Myl2, Myl3, Myh7, Atp2a1, Tpm1, Tpm2, and Ttn (Figure 10).