A prospective observational study, carried out in Slovenia from 2007 to 2012 on 717 patients with TBE by Bogovič P. et al. indicated that patients of an older age, without a previous vaccination against TBE, higher blood leukocyte count, higher serum C-reactive protein levels and a low level of specific TBEV serum IgG antibodies were linked to more severe courses of TBE [23]. Here, CRP is linked to tick-borne encephalitis.