Xu et al. reported that TAC improved refractory immune thrombocytopenia associated with pSS, which was attributed to its reductive effects on Th1 cytokine expression [52]; however, the effects of TAC on RA with sSS or RA positive for anti-Ro/SS-A antibodies are yet to be analyzed. The gene discussed is CALR; the disease is autoimmune thrombocytopenic purpura.