SOD1 and migraine disorder: Another important comorbidity to consider is hypovitaminosis D. A study evaluated the vitamin D, vitamin D-binding protein, vitamin D receptor (VITDR), high-sensitivity C-reactive protein, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), total antioxidant status (TAS), total oxidant status, and oxidative stress index values in 50 RRMS patients with migraine, 50 RRMS patients without migraine, and 50 healthy volunteers.