Regarding CRP, the study showed that high ln-CRP (natural log-transformed CRP) levels predicted a high risk of HF hospitalization [HR 1.64 (95% CI, 1.17–2.26); p = 0.004], and patients with high ln-CRP levels ≥ 4.25 (0.07 mg/dL) had a 3.68 times higher risk of HF hospitalization (p = 0.002) [67]. This evidence concerns the gene CRP and hydrops fetalis.