In PE, IgG/IgM and/or complement (C3) deposits are located not only in the intercellular spaces of the epidermis (typical for pemphigus) but also there are granular deposits of IgG or IgM and/or C3 along the dermal–epidermal junction (typical for lupus erythematosus) [7]. The gene discussed is CD40LG; the disease is lupus erythematosus.