Of interest, a recent study of cardiac ischemia–reperfusion animal models of delirium reported that pre-treatment with liraglutide, a long-acting glucagon-like peptide-1 (GLP-1), was protective against delirium behaviors via microglia mitophagy, neuroinflammation, and preserving synaptic integrity [126]. The gene discussed is GCG; the disease is delirium.