In agreement with the expected, we verified that rats fed fructose (10% in drinking water) for 18 weeks exhibit numerous features of MetS (including hypertension, hyperinsulinemia, hyperleptinemia, hypertriglyceridemia, higher angiotensin II blood levels, and higher hepatic triacylglycerides and fibrosis levels and liver: body ratio) and chrysin was able to revert some of the MetS characteristics induced by fructose-feeding, namely the hypertension, hepatic fibrosis, hyperinsulinemia, and the increase in angiotensin II serum levels [7]. The gene discussed is AGT; the disease is Hepatic fibrosis.