Several studies showed that curcumin is a compound capable of inhibiting the progression of bladder cancer cells by triggering apoptosis, inhibiting the PI3K/Akt pathway, blocking the Yes-associated protein (YAP) and/or WW domain–containing transcription regulator 1 (TAZ) pathway, affecting the cell cycle, and suppressing Extracellular signal-regulated kinase 1/2 (Erk1/2) and NF-κB signaling pathways [24]. The gene discussed is NFKB1; the disease is urinary bladder carcinoma.