It was also found that the proportion of insulin+/somatostatin+ cells correlated with the proportion of somatostatin+ cells in insulin-containing islets of children with T1D (Figure S2h), and the proportion of glucagon+/somatostatin+ cells correlated with the proportion of glucagon+ cells in insulin-containing islets of children with T1D (Figure S2e) and with the proportion of somatostatin+ cells in insulin-containing islets of children with T1D (Figure S2j) and in insulin-deficient islets (Figure S2l). The gene discussed is SST; the disease is type 1 diabetes mellitus.