The oral administration of EB-WE significantly reduced the levels of many types of cytokines (TNF-a, IL-6, IFN-g, IL-1b, IL-8) and chemokines (MCP-1, CXCL16, CXCL1, TARC) in BALF in the mice with ALI (Figure 6A). The gene discussed is CCL2; the disease is acute respiratory distress syndrome.