FLT3 and cancer: [1] Additionally, Cabozantinib targets other molecules such as ROS1, TRKA, TRKB, TYRO3 (FMS-like tyrosine kinase 3), the MER (TAM) family of receptor kinases, KIT, and FLT-3, which may contribute to its immune-modulating and anti-cancer effects [2,3,4].