DNM1L and hypertrophic cardiomyopathy: As for the hypertrophic cardiomyopathy (HC), which was the cause of death of our patient, it was reported in one of the two patients with the p.(Gly401Ser) [9] (Supplementary Table S1), in other three patients with a DNM1L pathogenic variant in the MD [44,49,62] and in one patient with a pathogenic variant in the GTPase domain [52] (Figure 3A).