NAT2 and systemic lupus erythematosus: An interesting study conducted in Japan identified an interaction between alcohol consumption and the N-acetyltransferase 2 (NAT2) genotype, as well as between NAT2 and alcohol consumption, indicating that individuals with the NAT2 rapid acetylation genotype and/or higher alcohol consumption have a lower risk of SLE compared to NAT2 slow acetylation [190].