Moreover, AD patients also present difficulties with behavior such as poor judgement and issues with communication, and in the later stages of this disease, AD patients may present difficulty walking, speaking, and swallowing [13], all of which are associated with the accumulation of Aβ plaques outside neurons and tau inside neurons, leading to neuronal cell death, inflammation, and brain atrophy [14,15,16,17,18]. The gene discussed is MAPT; the disease is Alzheimer disease.