In response to DAMP or PAMP stimulation, keratinocytes can produce a range of proinflammatory cytokines, including IFN-β, IL-1β, IL-36, TNF, IL-6, IL-8, IL-25, and CXCL10, which help establish the inflammatory T cell phenotype characteristic of psoriasis [63]. Here, IL1B is linked to psoriasis.