A prognostic value of baseline Hcy-thiolactonase activity of serum PON1 and tHcy levels for all-cause mortality was examined in a prospective study involving Japanese patients (n = 315, 82.7% male, mean age 66 years) who underwent percutaneous coronary intervention for stable coronary artery disease or acute coronary syndrome [131]. This evidence concerns the gene PON1 and coronary artery disorder.