Although HMMR is expressed in the peripheral blood of healthy controls, it is not comparable with its expression in leukemia patients, as we have observed in our findings (Figure 4C), which suggests that this gene is deregulated in B-ALL; however, we do not know which cells express HMMR in healthy peripheral blood because we do not perform cell sorting, and this will be a topic of future research. The gene discussed is HMMR; the disease is leukemia.