Table 2 shows that mutations on the genes APC, KRAS, TP53, PIK3CA, FBXW7, and SOX9 appeared with different rates in the individual samples of groups, by 6/6 (NAT) and 6/7 (CRC), 5/6 (NAT) and 5/7 (CRC), 5/6 (NAT) and 4/7 (CRC), 3/6 (NAT) and 5/7 (CRC), 5/6 (NAT) and 5/7 (CRC), 2/6 (NAT) and 4/7 (CRC) for APC, KRAS, TP53, PIK3CA, FBXW7, and SOX9, respectively. The TTN gene was an exception with its unique mutation rate of 100% (6/6 (NAT) and 7/7 (CRC)). The gene discussed is PIK3CA; the disease is colorectal carcinoma.