miR-200c has been shown to target NIMA-related kinase 7 (NEK7) to inhibit the activation of the NOD-like receptor 3 (NLRP3) inflammasome, thereby reducing cellular inflammation and suppressing pyroptosis in mouse epithelial cells, which in turn improves experimental models of inflammatory bowel disease [60]. The gene discussed is NEK7; the disease is inflammatory bowel disease.