Analysis of relative AR, PCA3, and PSMA mRNA expression in urine discovered a significant increase in PSMA (p ≤ 0.001) and PCA3 (p ≤ 0.05) expression in clinically significant PCa when compared with clinically insignificant PCa cases, if classified as pathological stage pT3 (Figure 1 and Figure S1a), as well as significant associations between PSMA expression and tumor grade (grade 1 vs. grade 3 p = 0.005, grade 1 vs. grade 2 p = 0.011) (Figure S2a). Here, PCA3 is linked to neoplasm.