CD8A and Huntington disease: In addition, an overall tendency towards lower TCRαβ+ T-cell counts was found in SARS-CoV-2 naïve non-MBL HD at day +30 after the second dose of the vaccine, which was significantly lower for TCRαβ+CD8+ T-cell numbers in the blood compared to previously infected non-MBL HD (0.02-fold decrease vs. 0.08-fold increase) (Figure 2).