Gene expression of HIF1α [35], which promotes the development of drug resistance in pancreatic cancer cell lines, and cytosolic NADPH dehydrogenase 1 (malic enzyme 1, ME1) [50,51], which promotes glutaminolysis and is related to stemness in oral cancer cells, were increased in HT29R and CT26R cells, whereas only HIF1α showed increased expression in CT26R cells (Figure 5D). Here, ME1 is linked to lip and oral cavity carcinoma.