It is worth mentioning that although the role of NF-κB as an anti-apoptotic and pro-survival agent in cancer has been previously shown, several in vitro and in vivo investigations reported an anti-tumorigenic and pro-apoptotic potential of this gene via different mechanisms in other types of cancer such as skin, liver, and ovarian [76,81,82,83,84,85,86,87,88,89]. This evidence concerns the gene NFKB1 and cancer.