Markers of endothelial damage have also been detected, such as elevated levels of selectin E and von Willebrand factor (vWF), which are associated with vascular dysfunction and thrombosis in patients with severe COVID-19, and coagulation markers (D-dimer and fibrinogen) related to the risk of thromboembolic events and disseminated intravascular coagulopathy [28,29,30]. This evidence concerns the gene VWF and COVID-19.