INS and type 2 diabetes mellitus: Other upregulated miRNAs like hsa-miR-26b-5p, hsa-miR-570-3p, hsa-miR-191-5p and hsa-miR-181a-5p were found to be involved in insulin signaling and resistance, glycemic impairment and significant risk for T2D [24,34,40,41,42,77].